| Route |
Origin |
Destination |
|
| JNB-ISL | (JNB) OR Tambo International Airport | (ISL) Atatürk International Airport | Johannesburg, ZA (JNB) to Istanbul, TR (ISL) |
| JNB-MTS | (JNB) OR Tambo International Airport | (MTS) Matsapha Airport | Johannesburg, ZA (JNB) to Manzini, SZ (MTS) |
| JNB-SZX | (JNB) OR Tambo International Airport | (SZX) Shenzhen Bao'an International Airport | Johannesburg, ZA (JNB) to Shenzhen, CN (SZX) |
| JNB-GAN | (JNB) OR Tambo International Airport | (GAN) Gan International Airport | Johannesburg, ZA (JNB) to Gan, MV (GAN) |
| JNB-TLE | (JNB) OR Tambo International Airport | (TLE) Toliara Airport | Johannesburg, ZA (JNB) to TLE |
| JNB-EZE | (JNB) OR Tambo International Airport | (EZE) Ministro Pistarini International Airport | Johannesburg, ZA (JNB) to Buenos Aires, AR (EZE) |
| JNB-FCO | (JNB) OR Tambo International Airport | (FCO) Leonardo da Vinci–Fiumicino Airport | Johannesburg, ZA (JNB) to Rome, IT (FCO) |
| JNB- | (JNB) OR Tambo International Airport | () Total Rf Heliport | Johannesburg, ZA (JNB) to Bensalem, US () |
| JNB-AMM | (JNB) OR Tambo International Airport | (AMM) Queen Alia International Airport | Johannesburg, ZA (JNB) to Amman, JO (AMM) |
| JNB-HAV | (JNB) OR Tambo International Airport | (HAV) José Martí International Airport | Johannesburg, ZA (JNB) to Havana, CU (HAV) |